Actin, Smooth Muscle

Ref: AP10010 – Clone: 1A4 – Host: Mouse – Method: P – Format: Ready to use

SKU: AP10010 Category: Tag:

Description

SUMMARY, EXPLANATION AND LIMITATIONS:

This antibody reacts with the alpha isoform of actin from muscle origin, specifically to smooth muscle. It doesn´t show any cross-reactivity with skeletal muscle actin and cardiac muscle as well as other epithelial and mesenchymal cells. Neither reacts with other components of the cytoskeleton.

Clone: 1A4

Isotype: IgG2a/kappa.

Immunogen: N-terminal decapeptide of alpha isoform smooth muscle actin, acetylated at the amino-terminus.

Staining pattern: Cytoplasmic.

Positive control: Tissue sample from smooth muscle, leiomyoma, leiomyosarcoma or blood vessels.

APPLICATIONS:

This antibody is designed for the specific location of the human protein smooth muscle actin by IHC techniques in buffered formalin-fixed tissues and paraffin embedded.

This antibody provides a useful tool for studying the intracellular distribution of actin and its role in the contractile system.