SUMMARY, EXPLANATION AND LIMITATIONS:
CD23 is a 45kDa glycoprotein, which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic
lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma.
Immunogen: Recombinant protein encoding human CD23 48-248aa.
Staining pattern: Cell membrane.
Positive control: Tissue sample from tonsil.
This antibody is designed for the specific localization of human CD23 using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.