SUMMARY, EXPLANATION AND LIMITATIONS:
CD45RB is expressed on mature B lymphocytes and the majority of lymphomas and leukemias of B-cell origin. This antigen is also expressed on the surface of cells of myeloid lineage and in the cytoplasm of tissue macrophage.
Immunogen: Human peripheral blood lymphocytes maintained in T cell growth factor.
Staining pattern: Cell membrane.
Positive control: Tissue sample from tonsil or lymph node.
This antibody is designed for the specific localization of human CD45RB using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.