SUMMARY, EXPLANATION AND LIMITATIONS:
Antibody to the lambda light chain of immunoglobulin is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Immunogen: Lambda light chains purified from human Bence Jones proteins.
Staining pattern: Cytoplasmic.
Positive control: Tissue sample from tonsil.
This antibody is designed for the specific localization of human lambda light chain using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.
This antibody is useful for identifying leukemias, plasmacytomas and certain non-Hodgkin lymphomas. The demonstration of clonality in lymphomas infiltrating indicates that infiltration is also clonal and malignant.