SDHB

Host Mouse
Clone zm211
Format Concentrate
Method IHC
Pretreatment Citrate or Edta
Positive Control Lymph Node of Hairy Cell Leukemia
Dilution 1:100 – 1:200
Isotype IgG2AILC
Inmunogen Recombinant Full-Length Human Annexin
Localization Nucleous, Cytoplasm or full Membrane
SKU: AP100229 Category:
 

Description

Complex II (succinate-ubiquinone oxidoreductase) is a mitochondrial enzyme complex that regulates aerobic respiration and TCA cycle. It is the smallest mitochondrial respiratory chain complex and consists of four subunits, namely, SDHA, SDHB, SDHC, and SDHD. Germline mutations in SDHB have been associated with invasive paragangliomas and pheochromocytomas . Anti-SDHB antibody is specific for SDHB in humans.

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