SUMMARY, EXPLANATION AND LIMITATIONS:
Antibodies in this cocktail recognize two different localizations of human thyroglobulin. It recognize human, rat and murine thyroglobulin.
Isotype: IgG1+ IgG1
Immunogen: Human purified thyroglobulin.
Staining pattern: Cytoplasmic.
Positive control: Tissue sample from thyroid.
This antibody is designed for the specific localization of human thyroglobulin using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.
Thyroglobulin immunohistochemical demonstration can be used for identifying thyroid neoplasms (papillary carcinomas, follicle carcinomas), especially in metastatic cases for determinate the thyroid origin. Non-thyroid originated adenocarcinomas are negative for this antibody. It also idenetifies heterotopic normal thyroid tissue (ovarian stroma).